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Question English Answer English
Protein
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A biological molecule made of amino acids and produced by ribosomes according to genetic instructions
Eukaryotic organism
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An organism whose cells have a nucleus and membrane-bound organelles
Cytosol
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The aqueous part of the cytoplasm of a cell; the cytoplasm excluding organelles
Prokaryotic organism
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A single-celled organism whose nucleic acid is not contained in a membrane-bound nucleus
DNA
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Deoxyribonucleic Acid (DNA) is a thread-like chain of nucleotides carrying the genetic instructions of an organism in a double helix of antiparallel strands
Nucleotides
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Organic molecules that are the building blocks of DNA; made of a sugar-phosphate backbone and nitrogenous bases
Double helix
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A pair of helices wound around a central axis; the shape of a DNA molecule
Nitrogenous base
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Nitrogen-containing molecule that forms part of the structure of a nucleotide
Leading strand
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The exposed strand of an unwound DNA molecule that runs in a 5' to 3' direction towards the replication fork
Lagging strand
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The exposed strand of an unwound DNA molecule that runs in a 5' to 3' direction away from the replication fork
Daughter Cells
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The two cells produced after a parent cell undergoes cell division
DNA Helicase
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The enzyme responsible for breaking hydrogen bonds between nitrogenous bases to unwind the DNA double helix into separate strands
DNA polymerase
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The enzyme responsible for matching and binding free-floating nucleotides to exposed nucleotides on unwound DNA strands
Free-floating nucleotides
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Nucleotides floating in the nucleoplasm or cytosol
Semi-conservative replication
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Replication of DNA resulting in two copies that each contain one of the original strands and one new strand
Sister chromatids
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The original and replicated chromosome joined by a centromere after DNA replication
Three-prime (3') end
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End of a nucleotide or DNA strand with the third carbon atom of the sugar molecule and a free hydroxyl group
Five-prime (5') end
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The end of a nucleotide or DNA strand with the fifth carbon atom of the sugar molecule and a free phosphate group
Replication fork
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The point of a DNA molecule where the helicase enzyme breaks hydrogen bonds between nitrogenous bases and exposes the two strands of DNA
Mitosis
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The process by which cells replicate during growth in multicellular organisms and reproduction in unicellular organisms
Gametes
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Reproductive cells in sexually reproducing organisms (e.g. sperm and egg)
Alleles
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Different forms of a gene found at the same locus in the genome of a species
Haploid cell
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A cell containing one of each chromosome required for the development of a new individual through sexual reproduction
Meiosis
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The process by which haploid sperm and egg cells are made from a diploid parent cell
Diploid cell
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A cell in which there are two of each chromosome present in the nucleous
Parent cell
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A cell that undergoes replication and division to produce identical daughter cells in mitosis or haploid gametes in meiosis
Crossing over
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The transfer of genes between homologous chromosomes during meiosis
Cytokinesis
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The division of a parent cell into two daughter cells as part of meiotic division
Seminiferous Tubules
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Tubules located in the male testes, the site of spermatogenesis
Spermatogonium
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A diploid parent cell that produces haploid sperm cells through meiosis
Spermatogenesis
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The process of haploid sperm cell production in males
Spermatocytes
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Diploid daughter cells produced from spermatogonia through mitotic division in the first stage of meiosis
Spermatid
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Immature haploid sperm cells
Spermatozoa
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Mature, motile sperm cells capable of fertilising an ovum
Oogonia
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Diploid parent cells that produce haploid egg cells through meiosis
Oogenesis
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The process of haploid egg cell production in females
Primary oocyte
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Diploid daughter cells produced from oogonia through meiotic division in the first stage of meiosis
Secondary oocyte
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Immature haploid egg cells
Polar body
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Cells produced during meiotic division in females that don't develop into gametes
Ovulation
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The release of a mature egg from the ovaries in preparation for fertilisation by a sperm cell
Gene Expression
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The process of producing a functional protein from the DNA code of a gene
Genes
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Sections of DNA that code for proteins; inherited from parent to offspring
Codon
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Series of three bases on an mRNA strand that will match with the anticodons on a tRNA molecule to determine amino acid selection
Amino acid
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The molecular building blocks of proteins
Translation
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Reading of an mRNA strand by a ribosome to form a polypeptide chain from amino acids
Noncoding DNA
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A section of DNA that doesn't code for a protein
RNA
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(ribonucleic acid); a single-stranded molecule of genetic information essential for protein synthesis
Transcription
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The production of an mRNA molecule from an unwound DNA double helix to be used for protein synthesis
mRNA
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(Messenger RNA); single stranded copy of one strand of DNA; carries the code required by a ribosome to build a polypeptide chain from amino acids
Initiation
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The process where DNA helicase breaks the hydrogen bonds between nitrogenous bases and the replication fork is formed
Elongation
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The process where RNA polymerase moves along the exposed DNA strand, using it as a template to build an mRNA strand from free-floating nucleotides
Termination
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The process of completing and releasing an mRNA molecule triggered by the ribosome reading a stop codon
Transcription Bubble
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A region of unwound DNA approximately 12-14 base pairs in length, produced by DNA helicase breaking hydrogen bonds between base pairs
Polypeptide chains
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A string of amino acids produced by a ribosome according to the genetic code provided by mRNA
Ribosomal Subunit
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One large and one small subunit molecule are required to assemble a functional ribosome for translation
tRNA
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(transfer RNA); A molecule that brings amino acids to a ribosome for translation and polypeptide production
Anticodon
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A sequence of three bases on a tRNA codon that correspond to an attached amino acid and matched an mRNA codon
Ribosome
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The organelle responsible for translation of the mRNA code into a polypeptide chain during protein synthesis
Condensation polymerisation reaction
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The reaction between amino acids joining them by a peptide link while releasing a water molecule
Cytoplasm
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Cell contents not including the nucleus
Epigenome
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A range of chemical compounds that alter genetic function while leaving the genetic sequence unaltered
Germ line
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Cells that form gametes and pass on genetic information from parent to offspring
Non-disjunction
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The failure of chromatids to separate during meiosis, causing aneuploidy in a gamete
Spindle fibres
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Long tubular structures produced by centrioles to attach to centromeres of chromosomes for separation in mitosis and meiosis
Aneuploidy
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The condition of a gamete that has an abnormal number of chromosomes
Karyotype
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An image of every chromosome of an organism, arranged to allow for comparison between chromosomes
Chromosome
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A structure of the cell nucleus containing DNA wound around histone proteins
Homologous pairs
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Corresponding chromosomes of the same shape in an individual produced through sexual reproduction; one of the chromosomes in the pair is inherited from the organism's father and the other from the organism's mother
Centromere
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The location on a chromosome where sister chromatids adjoin and spindle fibres attach to separate chromatids during cell division
Dominant Allele
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An allele that will be expressed phenotypically when paired with a recessive allele or another dominant allele
Recessive allele
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An allele that will be suppressed when paired with a dominant allele and will be expressed phenotypically when paired with another recessive allele
Genotype
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The combination of alleles for a particular trait present in an organism that determines its phenotype for that trait
Phenotype
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The trait expressed in an organism determined by its genotype
Punnett square
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A diagram used to predict likely percentages of genotype and phenotype of offspring based on the genotype of each parent
Autosomes
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Any chromosome that is not a sex chromosome
Autosomal dominance
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Dominance exhibited by any chromosome other than a sex chromosome causing traits or conditions to be expressed in the phenotype of an organism
Multiple Alleles
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Phenotypic traits controlled by more than two alleles
Recombinant DNA
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A DNA strand containing a genetic sequence artificially inserted in a laboratory
Target gene
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The gene that codes for the desired protein to be transferred between organisms
Donor organism
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The organism a target gene is removed from
Vector organism
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The organism that received the target gene into its genome to be expressed as a protein
Restriction enzyme
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An enzyme that breaks hydrogen bonds between nitrogenous bases at a particular sequence, leaving sticky ends
Recognition site
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The sequence of bases recognised by a restriction enzyme as the location to break hydrogen bonds and expose sticky ends
Sticky end
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The bases of a DNA molecule exposed when a restriction enzyme breaks hydrogen bonds between bases at a recognition site
Plasmid
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A circular molecule of DNA found in the cytoplasm of bacteria
PCR
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(Polymerase chain reaction); a technique that amplifies a short sequence of DNA
Gel electrophoresis
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A method of separating DNA or other biological molecules according to their molecular size
Evolution
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Changes in the phenotype of a species in response to selection pressures
Microevolution
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Changes in allele frequency across a population of a species
Macroevolution
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The accumulation of microevolutionary changes leading to long-term changes to a species, potentially leading to the emergence of one or more new species
Allele Frequency
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The number of times an allele appears in a population when compared with all other possible alleles for a trait
Bipedalism
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The ability of an animal to walk upright on two legs
Cranial capacity
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The volume of the skull; used as an indicator of brain size
Random mutations
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A change in the DNA sequence of an individual caused by random errors that occur during the DNA replication process
Homozygote
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An organism carrying two of the same allele for a trait, whether they be dominant or recessive
Heterozygote
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An organism carrying a combination of a dominant and a recessive allele for a trait, with the dominant phenotype expressed

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